Data Tier Applications (DAC) on replicated databases

We are exploring options to accomplish 3 things: 1) source control the database, 2) centralize and coordinate all database changes and tie them to application changes, and 3) automate database deployments. I'm considering using DACPACS for this but we have 4 production databases that have replication between themselves set in place. The replication was set up a long time ago and was implemented in an odd fashion. Essentially, not all 4 databases are exactly the same. Some data is replicated and some is not. My question is about applying DACPACS. If we were to apply the DACPACs to each database during a deployment, how would this affect replication? Thanks