Locking a table and disabling the indexes hangs mysql - 100% CPU

CREATE TABLE runs ( RunID int(11) NOT NULL DEFAULT '0', PRIMARY KEY (RunID) ) ENGINE=InnoDB DEFAULT CHARSET=latin1; -- -- Dumping data for table runs -- -- WHERE: runid=430864838 LOCK TABLES runs WRITE; ALTER TABLE runs DISABLE KEYS; INSERT INTO runs VALUES (430864838); As soon as

TABLE runs DISABLE KEYS;

runs it seems to hang the database - a core is 100% being used and it will not respond. What is the cause of this behavior?