How do you configure a 4-node AlwaysOn cluster to have two listeners?

Looking to build a 4-node (servers A, B, C & D) AlwaysOn Windows 2016 failover cluster with 2 nodes in the primary datacenter for HA, and 2 other replica nodes in the DR datacenter for disaster/reporting purposes. Since this is a multisite cluster, is there a way to configure to have two listeners (one for the Production/primary instance, the other for the DR instance) under the one AlwaysOn Availability Group. Also, would SQL on all four nodes need to run under the same service account? Or can servers A, B be on one account while servers C, D run under another account. Is this even feasible/possible? Thank you in advance for your help!! Hope everyone is safe & well during this time.