Restart master in physical replication

I have 2 servers involving master-slave replication (physical replication). I see the replication using select * from pg_replication_slots; there is a record saying : user : rep_user` application : 12/main state : streaming I have to change postgresql.conf on the master to enable pg_cron extension so I need to restart the master. Is it safe to just restart it using : sudo service postgresql stop followed by sudo service postgresql start ? Do I have to drop the replication first before restarting? thanks