[ODBC SQL Server Driver][DBNETLIB] SSL Security Error - Windows 2003 App Server to Remote SQL Server 2022 Connection

We have migrated the application databases from an old SQL Server 2000 instance running on Windows 2003 to a new SQL Server 2022 instance running on Windows 2022. The application tier has a number of web servers using IIS 6.0 on Windows 2003 and when they try to test the connection to the new SQL Server they get the below SSL security error. Any idea what could be the issue is here, is it likely to be the driver(screenshot below shows drivers installed on the web servers)? Or is it likely to be related to what versions of SSL/TLS are enabled on either side?