Changing SQL Server service account passwords enterprise-wide

In the event of a DBA leaving an organization, what options can the surviving team members pursue to change passwords for service accounts portfolio-wide? While using Configuration Manager appears to be the de-facto method, can PowerShell or another scripting or batch language be used to reset them in bulk? I figure if you're changing the login name for the service accounts, Configuration Manager is essential as registry permissions and the like need to be propagated. For just a password change to the existing account however, is a scriptable method OK as long as it's performed during approved maintenance windows for the service restarts?