File of Doom freezes any computer that attempts interaction

I have a file on an internal server that causes any machine that interacts with it to immediately and irrecoverably freeze. By interaction, I mean just about anything: rm, mv, cp, cat, vi, gedit, less, touch. (ls is fine.) Try any of these commands and the machine will completely halt: the GUI will freeze and all network connectivity goes down. The server hosting the file only goes down if a Windows machine attempts to interact with the file. The data server is mounted with Lustre and all the servers in question use RHEL 6. This is an internal, well-protected network, and the file was created within the network. There are many, many other files that have been created in a similar fashion that do no exhibit this problem. What could possibly be going on here? Is there some strange character sequence that causes Lustre or RHEL to flip out? I'm not a sysadmin, and I'm loathe to further interact with the file for fear of bringing down machines in active use for other purposes, but I'd like to know what's going on, how to remove the file if possible, or at least how to prevent creating another similar File of Doom.