modprobe fails with "Operation not permitted"

I am trying to modprobe wireguard as root, and it fails with: modprobe: ERROR: could not insert 'wireguard': Operation not permitted Adding verbose I get one more line: [root@localhost ben]# insmod /lib/modules/5.2.11-100.fc29.x86_64/extra/wireguard.ko.xz insmod: ERROR: could not insert module /lib/modules/5.2.11-100.fc29.x86_64/extra/wireguard.ko.xz: Operation not permitted dkms runs fine without error. I've also disabled selinux and that made no difference. I don't see anything in the journalctl logs. Looking through man pages and Google have not turned anything up. I did find this helpful line in dmesg: Lockdown: modprobe: Loading of unsigned module is restricted; see man kernel_lockdown.7 However that man page does not exist. How can I debug this? Any pointers on where to go next?