Odd input/output error running the latest version of Knoppix

I have this error when I try to do most things.. bash: /usr/bin/program: Input/output error This is a fresh install of the latest Knoppix, running off of a USB. The hash is correct, so I don't know what it really could be. Some dmesg output:

[ 1422.551305] cloop: decompression error -3 uncompressing block 12451 70223 bytes @ 1154490597, flags 0
[ 1422.551567] cloop: decompression error -3 uncompressing block 12451 70223 bytes @ 1154490597, flags 0
[ 1422.551832] cloop: decompression error -3 uncompressing block 12451 70223 bytes @ 1154490597, flags 0
[ 1422.552106] cloop: decompression error -3 uncompressing block 12451 70223 bytes @ 1154490597, flags 0
[ 1422.552367] cloop: decompression error -3 uncompressing block 12451 70223 bytes @ 1154490597, flags 0
[ 1422.552635] cloop: decompression error -3 uncompressing block 12451 70223 bytes @ 1154490597, flags 0
[ 1422.552907] cloop: decompression error -3 uncompressing block 12451 70223 bytes @ 1154490597, flags 0
[ 1422.553185] cloop: decompression error -3 uncompressing block 12451 70223 bytes @ 1154490597, flags 0
[ 1422.553476] cloop: decompression error -3 uncompressing block 12451 70223 bytes @ 1154490597, flags 0
[ 1422.553729] cloop: decompression error -3 uncompressing block 12451 70223 bytes @ 1154490597, flags 0
[ 1422.554017] cloop: decompression error -3 uncompressing block 12451 70223 bytes @ 1154490597, flags 0
[ 1422.554350] cloop: decompression error -3 uncompressing block 12451 70223 bytes @ 1154490597, flags 0
[ 1422.554678] cloop: decompression error -3 uncompressing block 12451 70223 bytes @ 1154490597, flags 0
[ 1481.701353] cloop: decompression error -3 uncompressing block 12451 70223 bytes @ 1154490597, flags 0
[ 1481.701356] print_req_error: 34 callbacks suppressed
[ 1481.701358] print_req_error: I/O error, dev cloop0, sector 6375040 flags 0
[ 1481.701615] cloop: decompression error -3 uncompressing block 12451 70223 bytes @ 1154490597, flags 0
[ 1481.701617] print_req_error: I/O error, dev cloop0, sector 6375040 flags 0
[ 1481.702060] cloop: decompression error -3 uncompressing block 12451 70223 bytes @ 1154490597, flags 0
[ 1481.702062] print_req_error: I/O error, dev cloop0, sector 6375216 flags 0
[ 1481.702319] cloop: decompression error -3 uncompressing block 12451 70223 bytes @ 1154490597, flags 0
[ 1481.702321] print_req_error: I/O error, dev cloop0, sector 6375216 flags 0
[ 1633.631162] cloop: decompression error -3 uncompressing block 12451 70223 bytes @ 1154490597, flags 0
[ 1633.631170] print_req_error: I/O error, dev cloop0, sector 6375040 flags 0
[ 1633.631815] cloop: decompression error -3 uncompressing block 12451 70223 bytes @ 1154490597, flags 0

Full dmesg output: http://0x0.st/i5py.json