using grep (or something similar) to find when rows are missing

I'm trying to find when certain rows are missing in a file. See below. In each record, there is an ItemNumber, MessageNumber, NewItemNumber, and ConfirmedQty field. Is there a way to find ItemNumber where NewItemNumber is missing, as in the last record here? 30353 000 30353 1 30354 000 30354 1 30391 000 30391 1 71067 000 71067 1 ** 29424 035 0 **