Is it possible to connect a serial port visible from userspace back into the kernel's BlueZ stack?

I have a linux kernel and device tree that presents the userspace with a serial port /dev/ttymxc0. The serial port is connected to a Bluetooth device which is used by a user-space Bluetooth stack. If the kernel has BlueZ compiled in, is it possible (e.g. by sysfs magic) to connect the serial port ttymxc0 to BlueZ such that it appears as an hci device? I know that I can do this by changing the device tree but wanted to know whether this was possible without rebooting with a different device tree?