How to 2-step authenticate by password + U2F Yubikey in Linux KeePassX?

I would like to have 2-step authentication by password + Fido U2F security key. I did not find any approaches which would work in Debian 8.7. The OS should not be a limiting factor here because Qt libraries are used with KeePassX . OS: Debian 8.7 Fido U2F key: YubiKey Neo, YubiKey 4