Virt-Manager won't start due to problem with libxml2 not importing in python

I have been happily using KVM and virt-manager on Arch Linux for about a year now. This morning, one of my VMs broke (that is another story which I don't think is related), and I decided that it would just be easiest to delete it and virt-install again. However, after deleting this VM via the virt-manager interface, I was no longer able to start virt-manager:

$ virt-install
Traceback (most recent call last):
  File "/usr/share/virt-manager/virt-install", line 15, in 
    import virtinst
  File "/usr/share/virt-manager/virtinst/__init__.py", line 49, in 
    from virtinst.domain import *  # pylint: disable=wildcard-import
  File "/usr/share/virt-manager/virtinst/domain/__init__.py", line 5, in 
    from .blkiotune import DomainBlkiotune
  File "/usr/share/virt-manager/virtinst/domain/blkiotune.py", line 8, in 
    from ..xmlbuilder import XMLBuilder, XMLChildProperty, XMLProperty
  File "/usr/share/virt-manager/virtinst/xmlbuilder.py", line 16, in 
    from .xmlapi import XMLAPI
  File "/usr/share/virt-manager/virtinst/xmlapi.py", line 7, in 
    import libxml2
  File "", line 991, in _find_and_load
  File "", line 975, in _find_and_load_unlocked
  File "", line 671, in _load_unlocked
  File "", line 779, in exec_module
  File "", line 911, in get_code
  File "", line 580, in _compile_bytecode
EOFError: marshal data too short

It seems that libxml2 is broken in some way:

Python 3.8.3 (default, May 17 2020, 18:15:42) 
[GCC 10.1.0] on linux
Type "help", "copyright", "credits" or "license" for more information.
>>> import libxml2
Traceback (most recent call last):
  File "", line 1, in 
  File "", line 991, in _find_and_load
  File "", line 975, in _find_and_load_unlocked
  File "", line 671, in _load_unlocked
  File "", line 779, in exec_module
  File "", line 911, in get_code
  File "", line 580, in _compile_bytecode
EOFError: marshal data too short

I have tried updating my system as well as removing and reinstalling the obvious packages, libvirt, virt-manager, libxml2 and libvirt-python, and that has not helped, nor has the somewhat dangerous pacman -Syyu. Any ideas about what might be broken here? I am using the LTS kernel, 5.4. Python version is 3.8. Virt-manager is 2.2.1 Also, if I just start python, I can load all the modules mentioned in the above error without any issue. I'm close to just doing a clean reinstall, but that is a terrible bother, and I'd like to avoid it if I can just fix some dependencies in Arch edit: As suggested in the comment, I tried running strace and here is the output (perhaps if I look at it long enough I will have some insight about which file might be corrupted). File corruption does seem likely as I ran out of disk space on root.

~]$ strace python -c 'import libxml2'
#output was too big to paste in here, so I cut out everything but the last part, which is what seemed most likely to be relevant
###..........many lines deleted....####
###..........many lines deleted....####
###..........many lines deleted....####
getcwd("/home/boss", 1024)              = 11
stat("/home/boss", {st_mode=S_IFDIR|0750, st_size=3488, ...}) = 0
stat("/home/boss", {st_mode=S_IFDIR|0750, st_size=3488, ...}) = 0
stat("/home/boss", {st_mode=S_IFDIR|0750, st_size=3488, ...}) = 0
openat(AT_FDCWD, "/home/boss", O_RDONLY|O_NONBLOCK|O_CLOEXEC|O_DIRECTORY) = 3
fstat(3, {st_mode=S_IFDIR|0750, st_size=3488, ...}) = 0
getdents64(3, /* 41 entries */, 32768)  = 1416
getdents64(3, /* 0 entries */, 32768)   = 0
close(3)                                = 0
stat("/usr/lib/python3.8", {st_mode=S_IFDIR|0755, st_size=8192, ...}) = 0
stat("/usr/lib/python3.8/lib-dynload", {st_mode=S_IFDIR|0755, st_size=8192, ...}) = 0
stat("/home/boss/.local/lib/python3.8/site-packages", {st_mode=S_IFDIR|0700, st_size=3488, ...}) = 0
stat("/usr/lib/python3.8/site-packages", {st_mode=S_IFDIR|0755, st_size=8192, ...}) = 0
stat("/usr/lib/python3.8/site-packages/libxml2.py", {st_mode=S_IFREG|0644, st_size=345896, ...}) = 0
stat("/usr/lib/python3.8/site-packages/libxml2.py", {st_mode=S_IFREG|0644, st_size=345896, ...}) = 0
openat(AT_FDCWD, "/usr/lib/python3.8/site-packages/__pycache__/libxml2.cpython-38.pyc", O_RDONLY|O_CLOEXEC) = 3
fstat(3, {st_mode=S_IFREG|0644, st_size=139264, ...}) = 0
ioctl(3, TCGETS, 0x7fffbe383200)        = -1 ENOTTY (Inappropriate ioctl for device)
lseek(3, 0, SEEK_CUR)                   = 0
lseek(3, 0, SEEK_CUR)                   = 0
fstat(3, {st_mode=S_IFREG|0644, st_size=139264, ...}) = 0
mmap(NULL, 143360, PROT_READ|PROT_WRITE, MAP_PRIVATE|MAP_ANONYMOUS, -1, 0) = 0x7f2172e15000
read(3, "U\r\r\n\0\0\0\0\203\224\246^(G\5\0\343\0\0\0\0\0\0\0\0\0\0\0\0\0\0\0"..., 139265) = 139264
read(3, "", 1)                          = 0
close(3)                                = 0
mmap(NULL, 262144, PROT_READ|PROT_WRITE, MAP_PRIVATE|MAP_ANONYMOUS, -1, 0) = 0x7f2172dd5000
write(2, "Traceback (most recent call last"..., 35Traceback (most recent call last):
) = 35
write(2, "  File \"\", line 1, in ", line 1, in 
) = 39
openat(AT_FDCWD, "", O_RDONLY|O_CLOEXEC) = -1 ENOENT (No such file or directory)
openat(AT_FDCWD, "", O_RDONLY|O_CLOEXEC) = -1 ENOENT (No such file or directory)
openat(AT_FDCWD, "/usr/lib/python38.zip/", O_RDONLY|O_CLOEXEC) = -1 ENOENT (No such file or directory)
openat(AT_FDCWD, "/usr/lib/python3.8/", O_RDONLY|O_CLOEXEC) = -1 ENOENT (No such file or directory)
openat(AT_FDCWD, "/usr/lib/python3.8/lib-dynload/", O_RDONLY|O_CLOEXEC) = -1 ENOENT (No such file or directory)
openat(AT_FDCWD, "/home/boss/.local/lib/python3.8/site-packages/", O_RDONLY|O_CLOEXEC) = -1 ENOENT (No such file or directory)
openat(AT_FDCWD, "/usr/lib/python3.8/site-packages/", O_RDONLY|O_CLOEXEC) = -1 ENOENT (No such file or directory)
write(2, "  File \"", line 991, in _find_and_load
) = 68
openat(AT_FDCWD, "", O_RDONLY|O_CLOEXEC) = -1 ENOENT (No such file or directory)
openat(AT_FDCWD, "", O_RDONLY|O_CLOEXEC) = -1 ENOENT (No such file or directory)
openat(AT_FDCWD, "/usr/lib/python38.zip/", O_RDONLY|O_CLOEXEC) = -1 ENOENT (No such file or directory)
openat(AT_FDCWD, "/usr/lib/python3.8/", O_RDONLY|O_CLOEXEC) = -1 ENOENT (No such file or directory)
openat(AT_FDCWD, "/usr/lib/python3.8/lib-dynload/", O_RDONLY|O_CLOEXEC) = -1 ENOENT (No such file or directory)
openat(AT_FDCWD, "/home/boss/.local/lib/python3.8/site-packages/", O_RDONLY|O_CLOEXEC) = -1 ENOENT (No such file or directory)
openat(AT_FDCWD, "/usr/lib/python3.8/site-packages/", O_RDONLY|O_CLOEXEC) = -1 ENOENT (No such file or directory)
write(2, "  File \"", line 975, in _find_and_load_unlocked
) = 77
openat(AT_FDCWD, "", O_RDONLY|O_CLOEXEC) = -1 ENOENT (No such file or directory)
openat(AT_FDCWD, "", O_RDONLY|O_CLOEXEC) = -1 ENOENT (No such file or directory)
openat(AT_FDCWD, "/usr/lib/python38.zip/", O_RDONLY|O_CLOEXEC) = -1 ENOENT (No such file or directory)
openat(AT_FDCWD, "/usr/lib/python3.8/", O_RDONLY|O_CLOEXEC) = -1 ENOENT (No such file or directory)
openat(AT_FDCWD, "/usr/lib/python3.8/lib-dynload/", O_RDONLY|O_CLOEXEC) = -1 ENOENT (No such file or directory)
openat(AT_FDCWD, "/home/boss/.local/lib/python3.8/site-packages/", O_RDONLY|O_CLOEXEC) = -1 ENOENT (No such file or directory)
openat(AT_FDCWD, "/usr/lib/python3.8/site-packages/", O_RDONLY|O_CLOEXEC) = -1 ENOENT (No such file or directory)
write(2, "  File \"", line 671, in _load_unlocked
) = 68
openat(AT_FDCWD, "", O_RDONLY|O_CLOEXEC) = -1 ENOENT (No such file or directory)
openat(AT_FDCWD, "", O_RDONLY|O_CLOEXEC) = -1 ENOENT (No such file or directory)
openat(AT_FDCWD, "/usr/lib/python38.zip/", O_RDONLY|O_CLOEXEC) = -1 ENOENT (No such file or directory)
openat(AT_FDCWD, "/usr/lib/python3.8/", O_RDONLY|O_CLOEXEC) = -1 ENOENT (No such file or directory)
openat(AT_FDCWD, "/usr/lib/python3.8/lib-dynload/", O_RDONLY|O_CLOEXEC) = -1 ENOENT (No such file or directory)
openat(AT_FDCWD, "/home/boss/.local/lib/python3.8/site-packages/", O_RDONLY|O_CLOEXEC) = -1 ENOENT (No such file or directory)
openat(AT_FDCWD, "/usr/lib/python3.8/site-packages/", O_RDONLY|O_CLOEXEC) = -1 ENOENT (No such file or directory)
write(2, "  File \"", line 779, in exec_module
) = 74
openat(AT_FDCWD, "", O_RDONLY|O_CLOEXEC) = -1 ENOENT (No such file or directory)
openat(AT_FDCWD, "", O_RDONLY|O_CLOEXEC) = -1 ENOENT (No such file or directory)
openat(AT_FDCWD, "/usr/lib/python38.zip/", O_RDONLY|O_CLOEXEC) = -1 ENOENT (No such file or directory)
openat(AT_FDCWD, "/usr/lib/python3.8/", O_RDONLY|O_CLOEXEC) = -1 ENOENT (No such file or directory)
openat(AT_FDCWD, "/usr/lib/python3.8/lib-dynload/", O_RDONLY|O_CLOEXEC) = -1 ENOENT (No such file or directory)
openat(AT_FDCWD, "/home/boss/.local/lib/python3.8/site-packages/", O_RDONLY|O_CLOEXEC) = -1 ENOENT (No such file or directory)
openat(AT_FDCWD, "/usr/lib/python3.8/site-packages/", O_RDONLY|O_CLOEXEC) = -1 ENOENT (No such file or directory)
write(2, "  File \"", line 911, in get_code
) = 71
openat(AT_FDCWD, "", O_RDONLY|O_CLOEXEC) = -1 ENOENT (No such file or directory)
openat(AT_FDCWD, "", O_RDONLY|O_CLOEXEC) = -1 ENOENT (No such file or directory)
openat(AT_FDCWD, "/usr/lib/python38.zip/", O_RDONLY|O_CLOEXEC) = -1 ENOENT (No such file or directory)
openat(AT_FDCWD, "/usr/lib/python3.8/", O_RDONLY|O_CLOEXEC) = -1 ENOENT (No such file or directory)
openat(AT_FDCWD, "/usr/lib/python3.8/lib-dynload/", O_RDONLY|O_CLOEXEC) = -1 ENOENT (No such file or directory)
openat(AT_FDCWD, "/home/boss/.local/lib/python3.8/site-packages/", O_RDONLY|O_CLOEXEC) = -1 ENOENT (No such file or directory)
openat(AT_FDCWD, "/usr/lib/python3.8/site-packages/", O_RDONLY|O_CLOEXEC) = -1 ENOENT (No such file or directory)
write(2, "  File \"", line 580, in _compile_bytecode
) = 80
openat(AT_FDCWD, "", O_RDONLY|O_CLOEXEC) = -1 ENOENT (No such file or directory)
openat(AT_FDCWD, "", O_RDONLY|O_CLOEXEC) = -1 ENOENT (No such file or directory)
openat(AT_FDCWD, "/usr/lib/python38.zip/", O_RDONLY|O_CLOEXEC) = -1 ENOENT (No such file or directory)
openat(AT_FDCWD, "/usr/lib/python3.8/", O_RDONLY|O_CLOEXEC) = -1 ENOENT (No such file or directory)
openat(AT_FDCWD, "/usr/lib/python3.8/lib-dynload/", O_RDONLY|O_CLOEXEC) = -1 ENOENT (No such file or directory)
openat(AT_FDCWD, "/home/boss/.local/lib/python3.8/site-packages/", O_RDONLY|O_CLOEXEC) = -1 ENOENT (No such file or directory)
openat(AT_FDCWD, "/usr/lib/python3.8/site-packages/", O_RDONLY|O_CLOEXEC) = -1 ENOENT (No such file or directory)
write(2, "EOFError: marshal data too short"..., 33EOFError: marshal data too short
) = 33
rt_sigaction(SIGINT, {sa_handler=SIG_DFL, sa_mask=[], sa_flags=SA_RESTORER, sa_restorer=0x7f21734763e0}, {sa_handler=0x7f21736ca3a2, sa_mask=[], sa_flags=SA_RESTORER, sa_restorer=0x7f21734763e0}, 8) = 0
munmap(0x7f2172dd5000, 262144)          = 0
munmap(0x7f2172e15000, 143360)          = 0
sigaltstack(NULL, {ss_sp=0x5610230bc580, ss_flags=0, ss_size=16384}) = 0
sigaltstack({ss_sp=NULL, ss_flags=SS_DISABLE, ss_size=0}, NULL) = 0
exit_group(1)                           = ?
+++ exited with 1 +++

edit: This thread seems promising, but I have no idea where I would check to see if __init__.py is missing.