Installing Pop OS on a system having two Hard-disks

I want to change from Windows to Pop OS, I don't want to make a partition and getting a dual boot, just want to say goodbye to Windows, the issue is that I'm not pretty sure if doing this having two Hard-disks (128GB+1TB), so, is it possible that I loose one Hard-disk on the process ? I'm worried to loose the 1TB Hard-disk (currently I'm working on my local C drive (the one of 128GB, so don't know if I can loose the 1TB of storage).