Apple Time Machine, Drobo and studio computer

I bought an Apple Time Machine. I have a home studio with several hard drives. I'm trying to find the best way to setup Time Machine to keep all my storage backed up all the time. Studio Computer (12 Core Mac Pro) - 250 GB - Internal SSD System Drive - 2 TB - Internal Media Drive (Audio Samples, Sample Instrument Files) - 2 TB - Internal Storage 1 (Recording Sessions) - 2 TB - Internal Storage 2 (Recording Sessions) - (Note: Internal Storage 1 & 2 are used until full and then they are stored away and new drives are purchased to replace them) MacBook Pro (13″ i7) - 250 GB - Internal SSD (OS X files and software only) - 1 TB - Internal Media (Audio Samples, Instruments, User Folder, Etc.) Questions: - What kind of setup do I need to back all of this up? - Do I need a big USB hub with a hard drive connected that mirrors every drive in my system? - Do those drives need to be larger than each of the primary drives? - Should I get a Drobo or some kind of RAID drive?