How to block pop-up ads

On some sites, when I click on a button a pop-up appeared, taking me to another website. The original website is still there, just that a new tab with ad site is opened and that interrupted my workflow. I had both enabled Adblock Plus (no whitelists) and disallowed pop-ups and redirects in the website setting (Google Chrome), but the pop-ups are not stopped. How can I prevent them? System: macOS High Sierra 10.13.6 Browser: Google Chrome 72.0.3626.119